C2010 | CAS:11028-71-0 | Concanavalin A Type IV | Con A | 刀豆球蛋A 四型

C2010   Concanavalin A from Canavalia ensiformis (Jack bean) Sigma        Type IV, lyophilized powder 货号 号 您的价格 RMB C2010-25MG 263.25 C2010-100MG 683.28 C2010-250MG 1,432.08 C2010-1G 3,242.07 Synonym: Con A CAS Number: 11028-71-0 EC Number: 234-258-2 MDL number: MFCD00071069 Description Analysis Note Where reported, agglutination activity is expressed in μg/ml and is determined from serial dilutions in phosphate buffered saline, pH 6.8, containing Ca2+ and Mn2+ of a 1 mg per mL solution. This activity is the lowest concentration to agglutinate a 2% suspension of human erythrocytes after 1 hr incubation at 25 °C. Biochem/physiol Actions Con A is not blood group specific but has an affinity for terminal α-D-mannosyl and α-D-glucosyl residues. Ca2+ and Mn2+ ions are required for activity. Con A dissociates into dimers at pH 5.6 or below. Between pH 5.8 and pH 7.0, Con A exists as a tetramer; above pH 7.0 higher aggregates are formed. Con A exhibits mitogenic activity which is dependent on its degree of aggregation. Succinylation results in an active dimeric form which remains a dimer above pH 5.6. Preparation Note Produced from whole Jack beans (J0250) using acetic acid by the method of Olson and Liener.1 Quality Highly purified 性质 type Type IV form lyophilized powder potency <64 μg per mL agglutination activity total impurities Carbohydrate, essentially free   salt, essentially free storage temp. −20°C 安全性 Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves Hazard Codes Xn Risk Statements 42/43 Safety Statements 24/25-36 WGK Germany 3 RTECS GK6890000