L4129 | CAS:9008-30-4 | L-α-Lysolecithin | 溶血卵磷脂

L4129  L-α-Lysophosphatidylcholine from egg yolk Sigma      ≥99%, Type I, powder 窗体底端 货号 号 您的价格 RMB L4129-25MG 558.09 L4129-100MG 1,413.36 L4129-500MG 5,153.85 L4129-1G 8,721.18 Synonym: 1-Acyl-sn-glycero-3-phosphocholine, L-α-Lysolecithin CAS Number: 9008-30-4 EC Number: 232-715-0 MDL number: MFCD00131444 Description Preparation Note Prepared by the action of phospholipase A on egg L-α-phosphatidylcholine. Quality Contains primarily palmitic and stearic acids. Biochem/physiol Actions Lysophosphatidylcholine is a major component of oxidized low density lipoproteins, and has been implicated in various inflammatory reactions, including atherosclerosis. It is used to demyelinate spinal neurons and study the processes underlying remyelination. It activates protein kinase C, p38 MAP kinase, p42 MAP Kinase, and the jun kinase (JNK) pathway, and stimulates transcription of c-jun. Lysophosphatidylcholine accumulates during cardiac ischemia and may induce arrhythmias by uncoupling gap junction communication, and increase ischemic damage by enhancing Na+ loading in cardiac myocytes. It also activates TREK1, TREK2 and TRAAK K+ channels. 性质 description zwitterionic type Type I assay ≥99% form powder color white storage temp. −20°C 安全性 Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter WGK Germany 3