C7268 | CAS:9076-44-2 | Chymostatin | 胰凝乳蛋白酶抑制剂

C7268  Chymostatin Sigma      microbial 窗体底端 货号 号 您的价格 RMB C7268-1MG 453.96 C7268-5MG 1,343.16 C7268-25MG 4,795.83 C7268-50MG 8,491.86 C7268-100MG 14,515.02 Synonym: N-(Nα-Carbonyl-Cpd-X-Phe-al)-Phe (Cpd = capreomycidine) (capreomycidine = [S,S]-α-(2-Iminohexahydro-4-pyrimidyl)glycine) CAS Number: 9076-44-2 MDL number: MFCD00071059 Description Biochem/physiol Actions Chymostatin is a strong inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases such as cathepsins A,B,C, B, H, and L. It weakly inhibits human leucocyte elastase. It is effective at a final concentration of 100 to 200 μg/ml (10 to 100 μM). Chymostatin is often included in protease inhibitor cocktails used with plant extracts. Other Notes A mixture of A (major), B and C components. A: X=Leu; B: X=Val; C: X=Ile chymostatin A MW = 607.7 chymostatin B MW = 593.7 chymostatin C MW = 607.7 Preparation Note Solubility testing in glacial acetic acid at 10 mg/ml yields a clear solution, which is usually colorless, but can be yellow in appearance. It is reportedly also soluble in DMSO; only slightly soluble in water and short-chain alcohols; insoluble in ethyl acetate, butyl acetate, ether, hexane, and petroleum ether. Stock solutions (10 mM) can be prepared in DMSO and are stable for months at -20 °C. Stock solutions can also be made in 0.1 M HCl. Dilute solutions (10-100 μM) are only stable for several hours, due to oxidation of the terminal aldehyde. 性质 biological source microbial solubility DMSO: soluble10 mM (Stock solutions stable for months at −20 °C.) storage temp. −20°C 安全性 Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter Safety Statements 22-24/25 WGK Germany 3 RTECS GC3047700